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Coordinated loading of IRG resistance GTPases on to the Toxoplasma gondii parasitophorous vacuole
The immunity-related GTPases (IRGs) constitute an interferon-induced intracellular resistance mechanism in mice against Toxoplasma gondii. IRG proteins accumulate on the parasitophorous vacuole membrane (PVM), leading to its disruption and to death of the parasite. How IRGs target the PVM is unknown...
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| 主要な著者: | , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Blackwell Publishing Ltd
2010
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2901525/ https://ncbi.nlm.nih.gov/pubmed/20109161 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1462-5822.2010.01443.x |
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