Coordinated loading of IRG resistance GTPases on to the Toxoplasma gondii parasitophorous vacuole

The immunity-related GTPases (IRGs) constitute an interferon-induced intracellular resistance mechanism in mice against Toxoplasma gondii. IRG proteins accumulate on the parasitophorous vacuole membrane (PVM), leading to its disruption and to death of the parasite. How IRGs target the PVM is unknown...

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Bibliografiska uppgifter
Huvudupphovsmän: Khaminets, Aliaksandr, Hunn, Julia P, Könen-Waisman, Stephanie, Zhao, Yang O, Preukschat, Daniela, Coers, Jörn, Boyle, Jon P, Ong, Yi-Ching, Boothroyd, John C, Reichmann, Gabriela, Howard, Jonathan C
Materialtyp: Artigo
Språk:Inglês
Publicerad: Blackwell Publishing Ltd 2010
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Original articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2901525/
https://ncbi.nlm.nih.gov/pubmed/20109161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1462-5822.2010.01443.x
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