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Disruption of the Toxoplasma gondii Parasitophorous Vacuole by IFNγ-Inducible Immunity-Related GTPases (IRG Proteins) Triggers Necrotic Cell Death

Toxoplasma gondii is a natural intracellular protozoal pathogen of mice and other small mammals. After infection, the parasite replicates freely in many cell types (tachyzoite stage) before undergoing a phase transition and encysting in brain and muscle (bradyzoite stage). In the mouse, early immune...

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Detalhes bibliográficos
Main Authors: Zhao, Yang O., Khaminets, Aliaksandr, Hunn, Julia P., Howard, Jonathan C.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2629126/
https://ncbi.nlm.nih.gov/pubmed/19197351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000288
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