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Coordinated loading of IRG resistance GTPases on to the Toxoplasma gondii parasitophorous vacuole

The immunity-related GTPases (IRGs) constitute an interferon-induced intracellular resistance mechanism in mice against Toxoplasma gondii. IRG proteins accumulate on the parasitophorous vacuole membrane (PVM), leading to its disruption and to death of the parasite. How IRGs target the PVM is unknown...

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Bibliografske podrobnosti
Main Authors: Khaminets, Aliaksandr, Hunn, Julia P, Könen-Waisman, Stephanie, Zhao, Yang O, Preukschat, Daniela, Coers, Jörn, Boyle, Jon P, Ong, Yi-Ching, Boothroyd, John C, Reichmann, Gabriela, Howard, Jonathan C
Format: Artigo
Jezik:Inglês
Izdano: Blackwell Publishing Ltd 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2901525/
https://ncbi.nlm.nih.gov/pubmed/20109161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1462-5822.2010.01443.x
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