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Dissecting microsatellite instability in colorectal cancer: one size does not fit all

Microsatellite instability (MSI) marks distinct subsets of tumors in many cancer types and is caused by mutations in genes required for mismatch repair. A recent report analyses the molecular foundations of MSI-positive colorectal cancers and reveals substantial molecular heterogeneity, which might...

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Detalhes bibliográficos
Publicado no:Genome Med
Main Authors: Samstein, Robert M., Chan, Timothy A.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5442871/
https://ncbi.nlm.nih.gov/pubmed/28539127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-017-0438-9
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