The DNA damage response in immunotherapy and radiation

Por Samstein, Robert M., Riaz, Nadeem
Publicado no Adv Radiat Oncol (2018)

Dissecting microsatellite instability in colorectal cancer: one size does not fit all

Por Samstein, Robert M., Chan, Timothy A.
Publicado no Genome Med (2017)

Advancing scientific knowledge in times of pandemics

Por Vabret, Nicolas, Samstein, Robert, Fernandez, Nicolas, Merad, Miriam
Publicado no Nat Rev Immunol (2020)

Locally Advanced and Unresectable Cutaneous Squamous Cell Carcinoma: Outcomes of Concurrent Cetuximab and Radiotherapy

Por Samstein, Robert M., Ho, Alan L., Lee, Nancy Y., Barker, Christopher A.
Publicado em 2014

Tumor mutational burden as a predictive biomarker for checkpoint inhibitor immunotherapy

Por Lee, Mark, Samstein, Robert M., Valero, Cristina, Chan, Timothy A., Morris, Luc G.T.
Publicado no Hum Vaccin Immunother (2019)

Extrathymic generation of regulatory T cells in placental mammals mitigates maternal-fetal conflict

Por Samstein, Robert M., Josefowicz, Steven Z., Arvey, Aaron, Treuting, Piper M., Rudensky, Alexander Y.
Publicado em 2012

CD4(+) regulatory T cells control Th17 responses in a Stat3-dependent manner

Por Chaudhry, Ashutosh, Rudra, Dipayan, Treuting, Piper, Samstein, Robert M., Liang, Yuqiong, Kas, Arnold, Rudensky, Alexander Y.
Publicado no Science (2009)

Inflammation-induced repression of Foxp3-bound chromatin in regulatory T cells

Por Arvey, Aaron, van der Veeken, Joris, Samstein, Robert M., Feng, Yongqiang, Stamatoyannopoulos, John A., Rudensky, Alexander Y.
Publicado em 2014

DNA Repair Gene Mutations as Predictors of Immune Checkpoint Inhibitor Response beyond Tumor Mutation Burden

Por Hsiehchen, David, Hsieh, Antony, Samstein, Robert M., Lu, Tianshi, Beg, Muhammad S., Gerber, David E., Wang, Tao, Morris, Luc G.T., Zhu, Hao
Publicado no Cell Rep Med (2020)

Localized Sinonasal Mucosal Melanoma: Outcomes and Associations with Stage, Radiotherapy and PET Response

Por Samstein, Robert M., Carvajal, Richard D., Postow, Michael A., Callahan, Margaret K., Shoushtari, Alexander N., Patel, Snehal G., Lee, Nancy Y., Barker, Christopher A.
Publicado no Head Neck (2016)

Transcription factor Foxp3 and its protein partners form a complex regulatory network

Por Rudra, Dipayan, deRoos, Paul, Chaudhry, Ashutosh, Niec, Rachel, Arvey, Aaron, Samstein, Robert M., Leslie, Christina, Shaffer, Scott A., Goodlett, David R., Rudensky, Alexander Y.
Publicado em 2012

Interleukin-10 signaling in regulatory T cells is required for suppression of Th17 cell-mediated inflammation

Por Chaudhry, Ashutosh, Samstein, Robert M., Treuting, Piper, Liang, Yuqiong, Pils, Marina C., Heinrich, Jan-Michael, Jack, Robert S., Wunderlich, F. Thomas, Brüning, Jens C., Müller, Werner, Rudensky, Alexander Y.
Publicado em 2011

Shared immunogenic poly-epitope frameshift mutations in microsatellite unstable tumors

Por Roudko, Vladimir, Bozkus, Cansu Cimen, Orfanelli, Theofano, McClain, Christopher B., Carr, Caitlin, O’Donnell, Timothy, Chakraborty, Lauren, Samstein, Robert, Huang, Kuan-lin, Blank, Stephanie V., Greenbaum, Benjamin, Bhardwaj, Nina
Publicado no Cell (2020)

Safety of combining thoracic radiation therapy with concurrent versus sequential immune checkpoint inhibition

Por von Reibnitz, Donata, Chaft, Jamie E., Wu, Abraham J., Samstein, Robert, Hellmann, Matthew D., Plodkowski, Andrew J., Zhang, Zhigang, Shi, Weiji, Dick-Godfrey, Rosalind, Panchoo, Kelly H., Barker, Christopher A., Rimner, Andreas
Publicado no Adv Radiat Oncol (2018)

Foxp3 exploits a preexistent enhancer landscape for regulatory T cell lineage specification

Por Samstein, Robert M., Arvey, Aaron, Josefowicz, Steven Z., Peng, Xiao, Reynolds, Alex, Sandstrom, Richard, Neph, Shane, Sabo, Peter, Kim, Jeong M., Liao, Will, O. Li, Ming, Leslie, Christina, Stamatoyannopoulos, John A., Rudensky, Alexander Y.
Publicado em 2012

Genomic Analyses for Predictors of Response to Chemoradiation in Stage III Non-Small Cell Lung Cancer

Por Luo, Leo Y., Samstein, Robert M., Dick-Godfrey, Rosalind, Sidiqi, Baho, Wang, Chunyu, Oro, Federica, Sonnick, Mark, Paik, Paul K., Chaft, Jamie E., Shaverdian, Narek, Gomez, Daniel R., Rimner, Andreas, Wu, Abraham J.
Publicado no Adv Radiat Oncol (2020)

AN ANTI-TUMOR IMMUNE RESPONSE IS EVOKED BY PARTIAL-VOLUME SINGLE DOSE RADIATION IN TWO MURINE MODELS

Por Markovsky, Ela, Budhu, Sadna, Samstein, Robert M., Li, Hongyan, Russell, James, Zhang, Zhigang, Drill, Esther, Bodden, Chloe, Chen, Qing, Powell, Simon N., Merghoub, Taha, Wolchok, Jedd D., Humm, John, Deasy, Joseph O., Haimovitz-Friedman, Adriana
Publicado no Int J Radiat Oncol Biol Phys (2018)

Luteinizing Hormone-Releasing Hormone Enhances T Cell Recovery following Allogeneic Bone Marrow Transplantation

Por Goldberg, Gabrielle L., King, Christopher G., Nejat, Rebecca A., Suh, David Y., Smith, Odette M., Bretz, Jamison C., Samstein, Robert M., Dudakov, Jarrod A., Chidgey, Ann P., Chen-Kiang, Selina, Boyd, Richard L., van den Brink, Marcel R. M.
Publicado em 2009

Patient HLA class I genotype influences cancer response to checkpoint blockade immunotherapy

Por Chowell, Diego, Morris, Luc G. T., Grigg, Claud M., Weber, Jeffrey K., Samstein, Robert M., Makarov, Vladimir, Kuo, Fengshen, Kendall, Sviatoslav M., Requena, David, Riaz, Nadeem, Greenbaum, Benjamin, Carroll, James, Garon, Edward, Hyman, David M., Zehir, Ahmet, Solit, David, Berger, Michael, Zhou, Ruhong, Rizvi, Naiyer A., Chan, Timothy A.
Publicado no Science (2017)

In situ vaccination with defined factors overcomes T cell exhaustion in distant tumors

Por Khalil, Danny N., Suek, Nathan, Campesato, Luis Felipe, Budhu, Sadna, Redmond, David, Samstein, Robert M., Krishna, Chirag, Panageas, Katherine S., Capanu, Marinela, Houghton, Sean, Hirschhorn, Daniel, Zappasodi, Roberta, Giese, Rachel, Gasmi, Billel, Schneider, Michael, Gupta, Aditi, Harding, James J., Moral, John Alec, Balachandran, Vinod P., Wolchok, Jedd D., Merghoub, Taha
Publicado no J Clin Invest (2019)