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The DNA damage response in immunotherapy and radiation

PURPOSE: Deficiencies in DNA damage repair (DDR) and response represent a common alteration in tumors, and exploitation of this feature using therapeutics has become more prominent. METHODS AND MATERIALS: Recent work has highlighted the important interaction between DDR defects, as well as DDR targe...

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Detalhes bibliográficos
Publicado no:Adv Radiat Oncol
Main Authors: Samstein, Robert M., Riaz, Nadeem
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6200889/
https://ncbi.nlm.nih.gov/pubmed/30370352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.adro.2018.08.017
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