Chimeric mice with humanized liver as a model for testing organophosphate and carbamate pesticide exposure

od Suemizu, Hiroshi, Kawai, Kenji, Murayama, Norie, Nakamura, Masato, Yamazaki, Hiroshi
izdano v Pest Manag Sci (2018)

Combining Chimeric Mice with Humanized Liver, Mass Spectrometry, And Physiologically-Based Pharmacokinetic Modeling in Toxicology

od Yamazaki, Hiroshi, Suemizu, Hiroshi, Mitsui, Marina, Shimizu, Makiko, Guengerich, F. Peter
izdano v Chem Res Toxicol (2016)

Simulation of Human Plasma Concentrations of Thalidomide and Primary 5-Hydroxylated Metabolites Explored with Pharmacokinetic Data in Humanized TK-NOG mice

od Nishiyama, Sayako, Suemizu, Hiroshi, Shibata, Norio, Guengerich, F. Peter, Yamazaki, Hiroshi
izdano v Chem Res Toxicol (2015)

Metabolic Profiles of Pomalidomide in Human Plasma Simulated with Pharmacokinetic Data in Control and Humanized-liver Mice

od Shimizu, Makiko, Suemizu, Hiroshi, Mitsui, Marina, Shibata, Norio, Guengerich, F. Peter, Yamazaki, Hiroshi
izdano v Xenobiotica (2016)

A basolateral sorting motif in the MICA cytoplasmic tail

od Suemizu, Hiroshi, Radosavljevic, Mirjana, Kimura, Minoru, Sadahiro, Sotaro, Yoshimura, Shinichi, Bahram, Seiamak, Inoko, Hidetoshi
Izdano 2002

Targeted sequencing reveals genetic variants associated with sensitivity of 79 human cancer xenografts to anticancer drugs

od Udagawa, Chihiro, Sasaki, Yasushi, Suemizu, Hiroshi, Ohnishi, Yasuyuki, Ohnishi, Hiroshi, Tokino, Takashi, Zembutsu, Hitoshi
izdano v Exp Ther Med (2018)

Comparative Transcriptomics Analyses in Livers of Mice, Humans, and Humanized Mice Define Human-Specific Gene Networks

od Jiang, Chengfei, Li, Ping, Ruan, Xiangbo, Ma, Yonghe, Kawai, Kenji, Suemizu, Hiroshi, Cao, Haiming
izdano v Cells (2020)

The human hepatic cell line HepaRG as a possible cell source for the generation of humanized liver TK-NOG mice

od Higuchi, Yuichiro, Kawai, Kenji, Yamazaki, Hiroshi, Nakamura, Masato, Bree, Françoise, Guguen-Guillouzo, Christiane, Suemizu, Hiroshi
Izdano 2014

In vivo Drug Interactions of the Teratogen Thalidomide with Midazolam: Heterotropic Cooperativity of Human Cytochrome P450 in Humanized TK-NOG Mice

od Yamazaki, Hiroshi, Suemizu, Hiroshi, Murayama, Norie, Utoh, Masahiro, Shibata, Norio, Nakamura, Masato, Guengerich, F. Peter
Izdano 2013

A Versatile Technique for the In Vivo Imaging of Human Tumor Xenografts Using Near-Infrared Fluorochrome-Conjugated Macromolecule Probes

od Suemizu, Hiroshi, Kawai, Kenji, Higuchi, Yuichiro, Hashimoto, Haruo, Ogura, Tomoyuki, Itoh, Toshio, Sasaki, Erika, Nakamura, Masato
Izdano 2013

A Novel Enhanced Green FluorescentProtein-Expressing NOG Mouse for Analyzingthe Microenvironment of Xenograft Tissues

od Higuchi, Yuichiro, Kawai, Kenji, Yamamoto, Masahumi, Kuronuma, Miyuki, Ando, Yasuhiko, Katano, Ikumi, Nakamura, Masato, Suemizu, Hiroshi
Izdano 2014

Hepatocytes buried in the cirrhotic livers of patients with biliary atresia proliferate and function in the livers of urokinase-type plasminogen activator–NOG mice

od Suemizu, Hiroshi, Nakamura, Kazuaki, Kawai, Kenji, Higuchi, Yuichiro, Kasahara, Mureo, Fujimoto, Junichiro, Tanoue, Akito, Nakamura, Masato
izdano v Liver Transpl (2014)

Whole-exome sequencing of 79 xenografts as a potential approach for the identification of genetic variants associated with sensitivity to cytotoxic anticancer drugs

od Udagawa, Chihiro, Sasaki, Yasushi, Tanizawa, Yasuhiro, Suemizu, Hiroshi, Ohnishi, Yasuyuki, Nakamura, Yasukazu, Tokino, Takashi, Zembutsu, Hitoshi
izdano v PLoS One (2020)

In Vivo Formation of a Glutathione Conjugate Derived from Thalidomide in Humanized uPA-NOG Mice

od Yamazaki, Hiroshi, Suemizu, Hiroshi, Igaya, Sho, Shimizu, Makiko, Shibata, Norio, Nakamura, Masato, Chowdhury, Goutam, Guengerich, F. Peter
Izdano 2011

In vivo Formation of Dihydroxylated and Glutathione Conjugate Metabolites derived from Thalidomide and 5-Hydroxythalidomide in Humanized TK-NOG mice

od Yamazaki, Hiroshi, Suemizu, Hiroshi, Shimizu, Makiko, Igaya, Sho, Shibata, Norio, Nakamura, Masato, Chowdhury, Goutam, Guengerich, F. Peter
Izdano 2012

Expression of pancreatic and duodenal homeobox1 (PDX1) protein in the interior and exterior regions of the intestine, revealed by development and analysis of Pdx1 knockout mice

od Hashimoto, Haruo, Kamisako, Tsutomu, Kagawa, Takahiro, Haraguchi, Seiki, Yagoto, Mika, Takahashi, Ri-ichi, Kawai, Kenji, Suemizu, Hiroshi
izdano v Lab Anim Res (2015)

ATP7B expression is associated with in vitro sensitivity to cisplatin in non-small cell lung cancer

od INOUE, YOSHIMASA, MATSUMOTO, HOZUMI, YAMADA, SHUNSUKE, KAWAI, KENJI, SUEMIZU, HIROSHI, GIKA, MASATOSHI, TAKANAMI, IWAO, NAKAMURA, MASATO, IWAZAKI, MASAYUKI
Izdano 2010

Association of ATP7A expression and in vitro sensitivity to cisplatin in non-small cell lung cancer

od INOUE, YOSHIMASA, MATSUMOTO, HOZUMI, YAMADA, SHUNSUKE, KAWAI, KENJI, SUEMIZU, HIROSHI, GIKA, MASATOSHI, TAKANAMI, IWAO, IWAZAKI, MASAYUKI, NAKAMURA, MASATO
Izdano 2010

Generation of Human Immunosuppressive Myeloid Cell Populations in Human Interleukin-6 Transgenic NOG Mice

od Hanazawa, Asami, Ito, Ryoji, Katano, Ikumi, Kawai, Kenji, Goto, Motohito, Suemizu, Hiroshi, Kawakami, Yutaka, Ito, Mamoru, Takahashi, Takeshi
izdano v Front Immunol (2018)

The Adult Livers of Immunodeficient Mice Support Human Hematopoiesis: Evidence for a Hepatic Mast Cell Population that Develops Early in Human Ontogeny

od Muench, Marcus O., Beyer, Ashley I., Fomin, Marina E., Thakker, Rahul, Mulvaney, Usha S., Nakamura, Masato, Suemizu, Hiroshi, Bárcena, Alicia
Izdano 2014