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The human hepatic cell line HepaRG as a possible cell source for the generation of humanized liver TK-NOG mice

1. Humanized-liver mice, in which the liver has been repopulated with human hepatocytes, have been used to study aspects of human liver physiology such as drug metabolism, toxicology and hepatitis infection. However, the procurement of human hepatocytes is a major problem in producing humanized-live...

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Bibliografski detalji
Glavni autori: Higuchi, Yuichiro, Kawai, Kenji, Yamazaki, Hiroshi, Nakamura, Masato, Bree, Françoise, Guguen-Guillouzo, Christiane, Suemizu, Hiroshi
Format: Artigo
Jezik:Inglês
Izdano: Informa UK Ltd. 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3906414/
https://ncbi.nlm.nih.gov/pubmed/24066694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/00498254.2013.836257
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