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The human hepatic cell line HepaRG as a possible cell source for the generation of humanized liver TK-NOG mice

1. Humanized-liver mice, in which the liver has been repopulated with human hepatocytes, have been used to study aspects of human liver physiology such as drug metabolism, toxicology and hepatitis infection. However, the procurement of human hepatocytes is a major problem in producing humanized-live...

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Detalhes bibliográficos
Main Authors: Higuchi, Yuichiro, Kawai, Kenji, Yamazaki, Hiroshi, Nakamura, Masato, Bree, Françoise, Guguen-Guillouzo, Christiane, Suemizu, Hiroshi
Formato: Artigo
Idioma:Inglês
Publicado em: Informa UK Ltd. 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3906414/
https://ncbi.nlm.nih.gov/pubmed/24066694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/00498254.2013.836257
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