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The human hepatic cell line HepaRG as a possible cell source for the generation of humanized liver TK-NOG mice

1. Humanized-liver mice, in which the liver has been repopulated with human hepatocytes, have been used to study aspects of human liver physiology such as drug metabolism, toxicology and hepatitis infection. However, the procurement of human hepatocytes is a major problem in producing humanized-live...

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Détails bibliographiques
Auteurs principaux: Higuchi, Yuichiro, Kawai, Kenji, Yamazaki, Hiroshi, Nakamura, Masato, Bree, Françoise, Guguen-Guillouzo, Christiane, Suemizu, Hiroshi
Format: Artigo
Langue:Inglês
Publié: Informa UK Ltd. 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3906414/
https://ncbi.nlm.nih.gov/pubmed/24066694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/00498254.2013.836257
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