The Reconstituted ‘Humanized Liver’ in TK-NOG Mice is Mature and Functional

To overcome the limitations of existing models, we developed a novel experimental in vivo platform for replacing mouse liver with functioning human liver tissue. To do this, a herpes simplex virus type 1 thymidine kinase (HSVtk) transgene was expressed within the liver of highly immunodeficient NOG...

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Библиографические подробности
Главные авторы: Hasegawa, Masami, Kawai, Kenji, Mitsui, Tetsuya, Taniguchi, Kenji, Monnai, Makoto, Wakui, Masatoshi, Ito, Mamoru, Suematsu, Makoto, Peltz, Gary, Nakamura, Masato, Suemizu, Hiroshi
Формат: Artigo
Язык:Inglês
Опубликовано: 2011
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3648850/
https://ncbi.nlm.nih.gov/pubmed/21238430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2011.01.042
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