NOD-Rag2(null) IL-2Rγ(null) Mice: An Alternative to NOG Mice for Generation of Humanized Mice

We have developed NOD-Rag2(null) IL-2Rγ(null) (NR2G) mice similar to NOD-scidIL-2Rγ(null) (NOG) mice that are known as an excellent host to generate humanized mice. To evaluate the usefulness of NR2G mice as a host for humanized mice, the engraftment rates and differentiation of human cells after hu...

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Main Authors: Katano, Ikumi, Ito, Ryoji, Kamisako, Tsutomu, Eto, Tomoo, Ogura, Tomoyuki, Kawai, Kenji, Suemizu, Hiroshi, Takahashi, Takeshi, Kawakami, Yutaka, Ito, Mamoru
Format: Artigo
Jezik:Inglês
Izdano: Japanese Association for Laboratory Animal Science 2014
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Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4206736/
https://ncbi.nlm.nih.gov/pubmed/25077762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1538/expanim.63.321
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