Incidence of spontaneous lymphomas in non-experimental NOD/Shi-scid, IL-2Rγ(null) (NOG) mice

Severely immunodeficient NOD/Shi-scid, IL-2Rγ(null) (NOG) mice provide an in vivo model for human cell/tissue transplantation studies. NOG mice were established by combining interleukin-2 receptor-γ chain knockout mice and NOD/Shi-scid mice. They exhibit a high incidence of thymic lymphomas and immu...

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Bibliographische Detailangaben
Veröffentlicht in:Exp Anim
Hauptverfasser: Yasuda, Masahiko, Ogura, Tomoyuki, Goto, Takayuki, Yagoto, Mika, Kamai, Yoko, Shimomura, Chie, Hayashimoto, Nobuhito, Kiyokawa, Yukito, Shinohara, Hideki, Takahashi, Riichi, Kawai, Kenji
Format: Artigo
Sprache:Inglês
Veröffentlicht: Japanese Association for Laboratory Animal Science 2017
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Original
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5682355/
https://ncbi.nlm.nih.gov/pubmed/28679969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1538/expanim.17-0034
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