Comparative Localization and Functional Activity of the Main Hepatobiliary Transporters in HepaRG Cells and Primary Human Hepatocytes

The role of hepatobiliary transporters in drug-induced liver injury remains poorly understood. Various in vivo and in vitro biological approaches are currently used for studying hepatic transporters; however, appropriate localization and functional activity of these transporters are essential for no...

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Dettagli Bibliografici
Pubblicato in:Toxicol Sci
Autori principali: Bachour-El Azzi, Pamela, Sharanek, Ahmad, Burban, Audrey, Li, Ruoya, Guével, Rémy Le, Abdel-Razzak, Ziad, Stieger, Bruno, Guguen-Guillouzo, Christiane, Guillouzo, André
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2015
Soggetti:
Transporters in HepaRG and Primary Human Hepatocytes
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4833040/
https://ncbi.nlm.nih.gov/pubmed/25690737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfv041
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