Comparative Localization and Functional Activity of the Main Hepatobiliary Transporters in HepaRG Cells and Primary Human Hepatocytes

The role of hepatobiliary transporters in drug-induced liver injury remains poorly understood. Various in vivo and in vitro biological approaches are currently used for studying hepatic transporters; however, appropriate localization and functional activity of these transporters are essential for no...

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Vydáno v:Toxicol Sci
Hlavní autoři: Bachour-El Azzi, Pamela, Sharanek, Ahmad, Burban, Audrey, Li, Ruoya, Guével, Rémy Le, Abdel-Razzak, Ziad, Stieger, Bruno, Guguen-Guillouzo, Christiane, Guillouzo, André
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2015
Témata:
Transporters in HepaRG and Primary Human Hepatocytes
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4833040/
https://ncbi.nlm.nih.gov/pubmed/25690737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfv041
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