Cellular and Molecular Effects of Prolonged Low-Level Sodium Arsenite Exposure on Human Hepatic HepaRG Cells

Inorganic arsenic is a human carcinogen associated with several types of cancers, including liver cancer. Inorganic arsenic has been postulated to target stem cells, causing their oncogenic transformation. This is proposed to be one of the key events in arsenic-associated carcinogenesis; however, th...

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Détails bibliographiques
Publié dans:Toxicol Sci
Auteurs principaux: Dreval, Kostiantyn, Tryndyak, Volodymyr, Kindrat, Iryna, Twaddle, Nathan C, Orisakwe, Orish Ebere, Mudalige, Thilak K, Beland, Frederick A, Doerge, Daniel R, Pogribny, Igor P
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2018
Sujets:
LOW DOSE SODIUM ARSENITE IN HepaRG CELLS
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5889046/
https://ncbi.nlm.nih.gov/pubmed/29301061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfx290
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