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Cellular and Molecular Effects of Prolonged Low-Level Sodium Arsenite Exposure on Human Hepatic HepaRG Cells

Inorganic arsenic is a human carcinogen associated with several types of cancers, including liver cancer. Inorganic arsenic has been postulated to target stem cells, causing their oncogenic transformation. This is proposed to be one of the key events in arsenic-associated carcinogenesis; however, th...

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Publicado en:Toxicol Sci
Main Authors: Dreval, Kostiantyn, Tryndyak, Volodymyr, Kindrat, Iryna, Twaddle, Nathan C, Orisakwe, Orish Ebere, Mudalige, Thilak K, Beland, Frederick A, Doerge, Daniel R, Pogribny, Igor P
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5889046/
https://ncbi.nlm.nih.gov/pubmed/29301061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfx290
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