Cellular and Molecular Effects of Prolonged Low-Level Sodium Arsenite Exposure on Human Hepatic HepaRG Cells

Inorganic arsenic is a human carcinogen associated with several types of cancers, including liver cancer. Inorganic arsenic has been postulated to target stem cells, causing their oncogenic transformation. This is proposed to be one of the key events in arsenic-associated carcinogenesis; however, th...

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Publicado en:Toxicol Sci
Autores principales: Dreval, Kostiantyn, Tryndyak, Volodymyr, Kindrat, Iryna, Twaddle, Nathan C, Orisakwe, Orish Ebere, Mudalige, Thilak K, Beland, Frederick A, Doerge, Daniel R, Pogribny, Igor P
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2018
Materias:
LOW DOSE SODIUM ARSENITE IN HepaRG CELLS
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5889046/
https://ncbi.nlm.nih.gov/pubmed/29301061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfx290
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