Cellular and Molecular Effects of Prolonged Low-Level Sodium Arsenite Exposure on Human Hepatic HepaRG Cells

Inorganic arsenic is a human carcinogen associated with several types of cancers, including liver cancer. Inorganic arsenic has been postulated to target stem cells, causing their oncogenic transformation. This is proposed to be one of the key events in arsenic-associated carcinogenesis; however, th...

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Udgivet i:Toxicol Sci
Main Authors: Dreval, Kostiantyn, Tryndyak, Volodymyr, Kindrat, Iryna, Twaddle, Nathan C, Orisakwe, Orish Ebere, Mudalige, Thilak K, Beland, Frederick A, Doerge, Daniel R, Pogribny, Igor P
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2018
Fag:
LOW DOSE SODIUM ARSENITE IN HepaRG CELLS
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5889046/
https://ncbi.nlm.nih.gov/pubmed/29301061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfx290
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