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Error-corrected next-generation sequencing mutagenicity assays in human HepaRG cells as human-relevant genetic toxicology new approach methodology

IntroductionHuman metabolically competent HepaRG™ (HepaRG) cells have been developed as a human-relevant New Approach Methodology (NAM) in genetic toxicology, providing a non-animal alternative to rodent-based mutagenicity testing following a positive Ames test. Error-corrected next-generation seque...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: A. Rasim Barutcu, Nimisha Bhattarai, Raymond Samuel, Jamie Scaglione, Leslie Recio
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Frontiers Media S.A. 2025-09-01
Saila:Frontiers in Toxicology
Gaiak:
Sarrera elektronikoa:https://www.frontiersin.org/articles/10.3389/ftox.2025.1657189/full
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