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Functional polarization of human hepatoma HepaRG cells in response to forskolin

HepaRG is an original human hepatoma cell line, acquiring highly differentiated hepatic features when exposed to dimethylsulfoxide (DMSO). To search alternatives to DMSO, which may exert some toxicity, we have analyzed the effects of forskolin (FSK), a cAMP-generating agent known to favor differenti...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Mayati, Abdullah, Moreau, Amélie, Le Vée, Marc, Bruyère, Arnaud, Jouan, Elodie, Denizot, Claire, Parmentier, Yannick, Fardel, Olivier
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6208432/
https://ncbi.nlm.nih.gov/pubmed/30382126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-34421-8
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