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Functional polarization of human hepatoma HepaRG cells in response to forskolin

HepaRG is an original human hepatoma cell line, acquiring highly differentiated hepatic features when exposed to dimethylsulfoxide (DMSO). To search alternatives to DMSO, which may exert some toxicity, we have analyzed the effects of forskolin (FSK), a cAMP-generating agent known to favor differenti...

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Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Mayati, Abdullah, Moreau, Amélie, Le Vée, Marc, Bruyère, Arnaud, Jouan, Elodie, Denizot, Claire, Parmentier, Yannick, Fardel, Olivier
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6208432/
https://ncbi.nlm.nih.gov/pubmed/30382126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-34421-8
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