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Drug Transporter Expression and Activity in Human Hepatoma HuH-7 Cells

Human hepatoma cells may represent a valuable alternative to the use of human hepatocytes for studying hepatic drug transporters, which is now a regulatory issue during drug development. In the present work, we have characterized hepatic drug transporter expression, activity and regulation in human...

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Detalhes bibliográficos
Publicado no:Pharmaceutics
Main Authors: Jouan, Elodie, Le Vée, Marc, Denizot, Claire, Parmentier, Yannick, Fardel, Olivier
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5374369/
https://ncbi.nlm.nih.gov/pubmed/28036031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics9010003
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