Functional polarization of human hepatoma HepaRG cells in response to forskolin

HepaRG is an original human hepatoma cell line, acquiring highly differentiated hepatic features when exposed to dimethylsulfoxide (DMSO). To search alternatives to DMSO, which may exert some toxicity, we have analyzed the effects of forskolin (FSK), a cAMP-generating agent known to favor differenti...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Mayati, Abdullah, Moreau, Amélie, Le Vée, Marc, Bruyère, Arnaud, Jouan, Elodie, Denizot, Claire, Parmentier, Yannick, Fardel, Olivier
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2018
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6208432/
https://ncbi.nlm.nih.gov/pubmed/30382126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-34421-8
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