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Expression of pancreatic and duodenal homeobox1 (PDX1) protein in the interior and exterior regions of the intestine, revealed by development and analysis of Pdx1 knockout mice

We developed pancreatic and duodenal homeobox1 (Pdx1) knockout mice to improve a compensatory hyperinsulinemia, which was induced by hyperplasia in the β cells or Langerhans' islands, as the diabetic model mice. For targeting of Pdx1 gene by homologous recombination, ES cells derived from a 129...

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Dettagli Bibliografici
Pubblicato in:Lab Anim Res
Autori principali: Hashimoto, Haruo, Kamisako, Tsutomu, Kagawa, Takahiro, Haraguchi, Seiki, Yagoto, Mika, Takahashi, Ri-ichi, Kawai, Kenji, Suemizu, Hiroshi
Natura: Artigo
Lingua:Inglês
Pubblicazione: Korean Association for Laboratory Animal Science 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4490151/
https://ncbi.nlm.nih.gov/pubmed/26155204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5625/lar.2015.31.2.93
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