Whole-exome sequencing of 79 xenografts as a potential approach for the identification of genetic variants associated with sensitivity to cytotoxic anticancer drugs

Chemotherapy response remains unpredictable in most patients with cancer. In this study, we performed whole-exome sequencing of 79 cancer xenografts derived from human cancer tissues to identify genetic predictors of chemosensitivity to nine cytotoxic anticancer drugs. Xenografts were harvested from...

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Foilsithe in:PLoS One
Main Authors: Udagawa, Chihiro, Sasaki, Yasushi, Tanizawa, Yasuhiro, Suemizu, Hiroshi, Ohnishi, Yasuyuki, Nakamura, Yasukazu, Tokino, Takashi, Zembutsu, Hitoshi
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2020
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7521756/
https://ncbi.nlm.nih.gov/pubmed/32986753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0239614
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