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The Adult Livers of Immunodeficient Mice Support Human Hematopoiesis: Evidence for a Hepatic Mast Cell Population that Develops Early in Human Ontogeny

The liver plays a vital role in hematopoiesis during mammalian prenatal development but its hematopoietic output declines during the perinatal period. Nonetheless, hepatic hematopoiesis is believed to persist into adulthood. We sought to model human adult-liver hematopoiesis by transplantation of fe...

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Detalhes bibliográficos
Main Authors: Muench, Marcus O., Beyer, Ashley I., Fomin, Marina E., Thakker, Rahul, Mulvaney, Usha S., Nakamura, Masato, Suemizu, Hiroshi, Bárcena, Alicia
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4018295/
https://ncbi.nlm.nih.gov/pubmed/24819392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0097312
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