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The Adult Livers of Immunodeficient Mice Support Human Hematopoiesis: Evidence for a Hepatic Mast Cell Population that Develops Early in Human Ontogeny

The liver plays a vital role in hematopoiesis during mammalian prenatal development but its hematopoietic output declines during the perinatal period. Nonetheless, hepatic hematopoiesis is believed to persist into adulthood. We sought to model human adult-liver hematopoiesis by transplantation of fe...

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Autors principals: Muench, Marcus O., Beyer, Ashley I., Fomin, Marina E., Thakker, Rahul, Mulvaney, Usha S., Nakamura, Masato, Suemizu, Hiroshi, Bárcena, Alicia
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4018295/
https://ncbi.nlm.nih.gov/pubmed/24819392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0097312
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