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Chimeric mice with humanized liver as a model for testing organophosphate and carbamate pesticide exposure

BACKGROUND: Diagnosis of acute intoxication with organophosphate (OP) or carbamate (CM) pesticides in humans is achieved by measuring plasma butyrylcholinesterase (BuChE) activity. However, BuChE activity is not an ideal biomarker in experimental animal models. The aim of this study was to establish...

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Detalhes bibliográficos
Publicado no:Pest Manag Sci
Main Authors: Suemizu, Hiroshi, Kawai, Kenji, Murayama, Norie, Nakamura, Masato, Yamazaki, Hiroshi
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Ltd 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5969263/
https://ncbi.nlm.nih.gov/pubmed/29235720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ps.4825
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