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Chimeric mice with humanized liver as a model for testing organophosphate and carbamate pesticide exposure

BACKGROUND: Diagnosis of acute intoxication with organophosphate (OP) or carbamate (CM) pesticides in humans is achieved by measuring plasma butyrylcholinesterase (BuChE) activity. However, BuChE activity is not an ideal biomarker in experimental animal models. The aim of this study was to establish...

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Publicado en:Pest Manag Sci
Autores principales: Suemizu, Hiroshi, Kawai, Kenji, Murayama, Norie, Nakamura, Masato, Yamazaki, Hiroshi
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley & Sons, Ltd 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5969263/
https://ncbi.nlm.nih.gov/pubmed/29235720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ps.4825
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