Chimeric mice with humanized liver as a model for testing organophosphate and carbamate pesticide exposure

BACKGROUND: Diagnosis of acute intoxication with organophosphate (OP) or carbamate (CM) pesticides in humans is achieved by measuring plasma butyrylcholinesterase (BuChE) activity. However, BuChE activity is not an ideal biomarker in experimental animal models. The aim of this study was to establish...

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Bibliographic Details
Published in:Pest Manag Sci
Main Authors: Suemizu, Hiroshi, Kawai, Kenji, Murayama, Norie, Nakamura, Masato, Yamazaki, Hiroshi
Format: Artigo
Language:Inglês
Published: John Wiley & Sons, Ltd 2018
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5969263/
https://ncbi.nlm.nih.gov/pubmed/29235720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ps.4825
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