Mechanistic Enzymology of the Radical SAM Enzyme DesII

по Ruszczycky, Mark W., Liu, Hung-wen
Опубликовано в: Isr J Chem (2015)

The surprising history of an antioxidant

по RUSZCZYCKY, MARK W., LIU, HUNG-WEN
Опубликовано в: Nature (2017)

Theory and Application of the Relationship between Steady-State Isotope Effects on Enzyme Intermediate Concentrations and Net Rate Constants()

по Ruszczycky, Mark W., Liu, Hung-wen
Опубликовано в: Methods Enzymol (2017)

Measurement of Net Rate Constants from Enzyme Progress Curves without Curve Fitting

по Ruszczycky, Mark W., Liu, Hung-wen
Опубликовано в: Biochemistry (2019)

Radical SAM enzymes in the biosynthesis of sugar-containing natural products(☆)

по Ruszczycky, Mark W., Ogasawara, Yasushi, Liu, Hung-wen
Опубликовано 2011

Following the electrons: Peculiarities in the catalytic cycles of Radical SAM enzymes

по Ruszczycky, Mark W., Zhong, Aoshu, Liu, Hung-wen
Опубликовано в: Nat Prod Rep (2018)

Changes in Regioselectivity of H Atom Abstraction during the Hydroxylation and Cyclization Reactions Catalyzed by Hyoscyamine 6β-Hydroxylase

по Ushimaru, Richiro, Ruszczycky, Mark W., Liu, Hung-wen
Опубликовано в: J Am Chem Soc (2018)

Stoichiometry of the Redox Neutral Deamination and Oxidative Dehydrogenation Reactions Catalyzed by the Radical SAM Enzyme DesII

по Ruszczycky, Mark W., Choi, Sei-hyun, Liu, Hung-wen
Опубликовано 2010

Current Developments and Challenges in the Search for a Naturally Selected Diels-Alderase

по Kim, Hak Joong, Ruszczycky, Mark W., Liu, Hung-wen
Опубликовано 2012

EPR-kinetic isotope effect study of the mechanism of radical-mediated dehydrogenation of an alcohol by the radical SAM enzyme DesII

по Ruszczycky, Mark W., Choi, Sei-hyun, Liu, Hung-wen
Опубликовано 2013

Mechanistic Studies of the Radical SAM Enzyme DesII with TDP-d-Fucose

по Ko, Yeonjin, Ruszczycky, Mark W., Choi, Sei-Hyun, Liu, Hung-wen
Опубликовано в: Angew Chem Int Ed Engl (2014)

Mechanistic Implications of the Deamination of TDP-4-amino-4-deoxy-d-fucose Catalyzed by the Radical SAM Enzyme DesII

по Ko, Yeonjin, Lin, Geng-Min, Ruszczycky, Mark W., Liu, Hung-wen
Опубликовано в: Biochemistry (2018)

Natural [4 + 2]-Cyclases

по Jeon, Byung-sun, Wang, Shao-An, Ruszczycky, Mark W., Liu, Hung-wen
Опубликовано в: Chem Rev (2016)

Mechanistic Studies of the Radical SAM Enzyme DesII: EPR Characterization of a Radical Intermediate Generated During Its Catalyzed Dehydrogenation of TDP-D-Quinovose

по Ruszczycky, Mark W., Choi, Sei-hyun, Mansoorabadi, Steven O., Liu, Hung-wen
Опубликовано 2011

Mechanistic Investigation of the Radical S-Adenosyl-l-methionine (SAM) Enzyme DesII Using Fluorinated Analogs

по Lin, Geng-Min, Choi, Sei-Hyun, Ruszczycky, Mark W., Liu, Hung-wen
Опубликовано в: J Am Chem Soc (2015)

Identification and Characterization of Enzymes Catalyzing Pyrazolopyrimidine Formation in the Biosynthesis of Formycin A

по Ko, Yeonjin, Wang, Shao-An, Ogasawara, Yasushi, Ruszczycky, Mark W., Liu, Hung-wen
Опубликовано в: Org Lett (2017)

Characterization and Mechanistic Studies of DesII: A Radical S-Adenosyl-L-methionine Enzyme Involved in the Biosynthesis of TDP-D-Desosamine

по Szu, Ping-Hui, Ruszczycky, Mark W., Choi, Sei-hyun, Yan, Feng, Liu, Hung-wen
Опубликовано 2009

An Enzyme-Catalyzed [4+2] Cycloaddition is a Key Step in the Biosynthesis of Spinosyn A

по Kim, Hak Joong, Ruszczycky, Mark W., Choi, Sei-hyun, Liu, Yung-nan, Liu, Hung-wen
Опубликовано 2011

Nucleophilic Participation of Reduced Flavin Coenzyme in Mechanism of UDP-galactopyranose Mutase

по Sun, He G., Ruszczycky, Mark W., Chang, Wei-chen, Thibodeaux, Christopher J., Liu, Hung-wen
Опубликовано 2012

Substrate Conformation Correlates with the Outcome of Hyoscyamine 6β-Hydroxylase Catalyzed Oxidation Reactions

по Ushimaru, Richiro, Ruszczycky, Mark W., Chang, Wei-chen, Yan, Feng, Liu, Yung-nan, Liu, Hung-wen
Опубликовано в: J Am Chem Soc (2018)