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Natural [4 + 2]-Cyclases

[4 + 2]-Cycloadditions are increasingly being recognized in the biosynthetic pathways of many structurally complex natural products. A relatively small collection of enzymes from these pathways have been demonstrated to increase rates of cyclization and impose stereochemical constraints on the react...

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Detalles Bibliográficos
Publicado en:Chem Rev
Autores principales: Jeon, Byung-sun, Wang, Shao-An, Ruszczycky, Mark W., Liu, Hung-wen
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6063532/
https://ncbi.nlm.nih.gov/pubmed/28441874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.chemrev.6b00578
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