Mechanistic Enzymology of the Radical SAM Enzyme DesII

Por Ruszczycky, Mark W., Liu, Hung-wen
Publicado no Isr J Chem (2015)

The surprising history of an antioxidant

Por RUSZCZYCKY, MARK W., LIU, HUNG-WEN
Publicado no Nature (2017)

Theory and Application of the Relationship between Steady-State Isotope Effects on Enzyme Intermediate Concentrations and Net Rate Constants()

Por Ruszczycky, Mark W., Liu, Hung-wen
Publicado no Methods Enzymol (2017)

Measurement of Net Rate Constants from Enzyme Progress Curves without Curve Fitting

Por Ruszczycky, Mark W., Liu, Hung-wen
Publicado no Biochemistry (2019)

Radical SAM enzymes in the biosynthesis of sugar-containing natural products(☆)

Por Ruszczycky, Mark W., Ogasawara, Yasushi, Liu, Hung-wen
Publicado em 2011

Following the electrons: Peculiarities in the catalytic cycles of Radical SAM enzymes

Por Ruszczycky, Mark W., Zhong, Aoshu, Liu, Hung-wen
Publicado no Nat Prod Rep (2018)

Changes in Regioselectivity of H Atom Abstraction during the Hydroxylation and Cyclization Reactions Catalyzed by Hyoscyamine 6β-Hydroxylase

Por Ushimaru, Richiro, Ruszczycky, Mark W., Liu, Hung-wen
Publicado no J Am Chem Soc (2018)

Stoichiometry of the Redox Neutral Deamination and Oxidative Dehydrogenation Reactions Catalyzed by the Radical SAM Enzyme DesII

Por Ruszczycky, Mark W., Choi, Sei-hyun, Liu, Hung-wen
Publicado em 2010

Current Developments and Challenges in the Search for a Naturally Selected Diels-Alderase

Por Kim, Hak Joong, Ruszczycky, Mark W., Liu, Hung-wen
Publicado em 2012

EPR-kinetic isotope effect study of the mechanism of radical-mediated dehydrogenation of an alcohol by the radical SAM enzyme DesII

Por Ruszczycky, Mark W., Choi, Sei-hyun, Liu, Hung-wen
Publicado em 2013

Mechanistic Studies of the Radical SAM Enzyme DesII with TDP-d-Fucose

Por Ko, Yeonjin, Ruszczycky, Mark W., Choi, Sei-Hyun, Liu, Hung-wen
Publicado no Angew Chem Int Ed Engl (2014)

Mechanistic Implications of the Deamination of TDP-4-amino-4-deoxy-d-fucose Catalyzed by the Radical SAM Enzyme DesII

Por Ko, Yeonjin, Lin, Geng-Min, Ruszczycky, Mark W., Liu, Hung-wen
Publicado no Biochemistry (2018)

Natural [4 + 2]-Cyclases

Por Jeon, Byung-sun, Wang, Shao-An, Ruszczycky, Mark W., Liu, Hung-wen
Publicado no Chem Rev (2016)

Mechanistic Studies of the Radical SAM Enzyme DesII: EPR Characterization of a Radical Intermediate Generated During Its Catalyzed Dehydrogenation of TDP-D-Quinovose

Por Ruszczycky, Mark W., Choi, Sei-hyun, Mansoorabadi, Steven O., Liu, Hung-wen
Publicado em 2011

Mechanistic Investigation of the Radical S-Adenosyl-l-methionine (SAM) Enzyme DesII Using Fluorinated Analogs

Por Lin, Geng-Min, Choi, Sei-Hyun, Ruszczycky, Mark W., Liu, Hung-wen
Publicado no J Am Chem Soc (2015)

Identification and Characterization of Enzymes Catalyzing Pyrazolopyrimidine Formation in the Biosynthesis of Formycin A

Por Ko, Yeonjin, Wang, Shao-An, Ogasawara, Yasushi, Ruszczycky, Mark W., Liu, Hung-wen
Publicado no Org Lett (2017)

Characterization and Mechanistic Studies of DesII: A Radical S-Adenosyl-L-methionine Enzyme Involved in the Biosynthesis of TDP-D-Desosamine

Por Szu, Ping-Hui, Ruszczycky, Mark W., Choi, Sei-hyun, Yan, Feng, Liu, Hung-wen
Publicado em 2009

An Enzyme-Catalyzed [4+2] Cycloaddition is a Key Step in the Biosynthesis of Spinosyn A

Por Kim, Hak Joong, Ruszczycky, Mark W., Choi, Sei-hyun, Liu, Yung-nan, Liu, Hung-wen
Publicado em 2011

Nucleophilic Participation of Reduced Flavin Coenzyme in Mechanism of UDP-galactopyranose Mutase

Por Sun, He G., Ruszczycky, Mark W., Chang, Wei-chen, Thibodeaux, Christopher J., Liu, Hung-wen
Publicado em 2012

Substrate Conformation Correlates with the Outcome of Hyoscyamine 6β-Hydroxylase Catalyzed Oxidation Reactions

Por Ushimaru, Richiro, Ruszczycky, Mark W., Chang, Wei-chen, Yan, Feng, Liu, Yung-nan, Liu, Hung-wen
Publicado no J Am Chem Soc (2018)