Načítá se...

Substrate Conformation Correlates with the Outcome of Hyoscyamine 6β-Hydroxylase Catalyzed Oxidation Reactions

Hyoscyamine 6β-hydroxylase (H6H) is an α-ketoglutarate dependent mononuclear nonheme iron enzyme that catalyzes C6-hydroxylation of hyoscyamine and oxidative cyclization of the resulting product to give the oxirane natural product scopolamine. Herein, the chemistry of H6H is investigated using hyosc...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:J Am Chem Soc
Hlavní autoři: Ushimaru, Richiro, Ruszczycky, Mark W., Chang, Wei-chen, Yan, Feng, Liu, Yung-nan, Liu, Hung-wen
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6488034/
https://ncbi.nlm.nih.gov/pubmed/29870653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.8b03729
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!