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Stoichiometry of the Redox Neutral Deamination and Oxidative Dehydrogenation Reactions Catalyzed by the Radical SAM Enzyme DesII

DesII from Streptomyces venezuelae is a radical SAM (S-adenosyl-l-methionine) enzyme that catalyzes the deamination of TDP-4-amino-4,6-dideoxy-d-glucose to form TDP-3-keto-4,6-dideoxy-d-glucose in the biosynthesis of TDP-d-desosamine. DesII also catalyzes the dehydrogenation of the non-physiological...

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Autors principals: Ruszczycky, Mark W., Choi, Sei-hyun, Liu, Hung-wen
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2833275/
https://ncbi.nlm.nih.gov/pubmed/20121093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja909451a
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