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Mechanistic Enzymology of the Radical SAM Enzyme DesII

DesII is a member of the radical SAM family of enzymes that catalyzes radical-mediated transformations of TDP-4-amino-4,6-didexoy-D-glucose as well as other sugar nucleotide diphosphates. Like nearly all radical SAM enzymes, the reactions begin with the reductive homolysis of SAM to produce a 5′-deo...

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Bibliographic Details
Published in:Isr J Chem
Main Authors: Ruszczycky, Mark W., Liu, Hung-wen
Format: Artigo
Language:Inglês
Published: 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5021314/
https://ncbi.nlm.nih.gov/pubmed/27635101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijch.201400130
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