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Characterization of, DNPH. Enzymes Catalyzing Transformations of Cysteine S-Conjugated Intermediates in the Lincosamide Biosynthetic Pathway

Lincosamides such as lincomycin A, celesticetin, and Bu-2545, constitute an important group of antibiotics. While these natural products are characterized by a thiooctose linked to a L-proline residue, they differ with regards to modification of the thioacetal moiety, the pyrrolidine ring, and the o...

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Publicado en:Chembiochem
Autores principales: Ushimaru, Richiro, Lin, Chia-I, Sasaki, Eita, Liu, Hung-wen
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5253346/
https://ncbi.nlm.nih.gov/pubmed/27431934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201600223
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