Nucleophilic Participation of Reduced Flavin Coenzyme in Mechanism of UDP-galactopyranose Mutase

UDP-galactopyranose mutase (UGM) requires reduced FAD (FAD(red)) to catalyze the reversible interconversion of UDP-galactopyranose (UDP-Galp) and UDP-galactofuranose (UDP-Galf). Recent structural and mechanistic studies of UGM have provided evidence for the existence of an FAD-Galf/p adduct as an in...

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Bibliografski detalji
Glavni autori: Sun, He G., Ruszczycky, Mark W., Chang, Wei-chen, Thibodeaux, Christopher J., Liu, Hung-wen
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2012
Teme:
Enzymology
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3281622/
https://ncbi.nlm.nih.gov/pubmed/22187430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.312538
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