Delineation of a Fundamental α-Ketoheterocycle Substituent Effect For Use in the Design of Enzyme Inhibitors

מאת Romero, F. Anthony, Hwang, Inkyu, Boger, Dale L.
יצא לאור 2006

Total Synthesis of Piericidin A1 and B1 and Key Analogues

מאת Schnermann, Martin J., Romero, F. Anthony, Hwang, Inkyu, Nakamaru-Ogiso, Eiko, Yagi, Takao, Boger, Dale L.
יצא לאור 2006

Structure–Activity Relationships of α-Keto Oxazole Inhibitors of Fatty Acid Amide Hydrolase

מאת Hardouin, Christophe, Kelso, Michael J., Romero, F. Anthony, Rayl, Thomas J., Leung, Donmienne, Hwang, Inkyu, Cravatt, Benjamin F., Boger, Dale L.
יצא לאור 2007

Optimization of α-Ketooxazole Inhibitors of Fatty Acid Amide Hydrolase

מאת Kimball, F. Scott, Romero, F. Anthony, Ezzili, Cyrine, Garfunkle, Joie, Rayl, Thomas J., Hochstatter, Dustin G., Hwang, Inkyu, Boger, Dale L.
יצא לאור 2008

Potent and Selective α-Ketoheterocycle-Based Inhibitors of the Anandamide and Oleamide Catabolizing Enzyme, Fatty Acid Amide Hydrolase

מאת Romero, F. Anthony, Du, Wu, Hwang, Inkyu, Rayl, Thomas J., Kimball, F. Scott, Leung, Donmienne, Hoover, Heather S., Apodaca, Richard L., Breitenbucher, J. Guy, Cravatt, Benjamin F., Boger, Dale L.
יצא לאור 2007

Optimization of Preclinical Metabolism for Somatostatin Receptor Subtype 5-Selective Antagonists

מאת Liu, Weiguo, Hussain, Zahid, Zang, Yi, Sweis, Ramzi F., Romero, F. Anthony, Finke, Paul E., Moningka, Remond, Bao, Jianming, Plotkin, Michael A., Shang, Jin, Dingley, Karen H., Salituro, Gino, Murphy, Beth Ann, Howard, Andrew D., Ujjainwalla, Feroze, Wood, Harold B., Duffy, Joseph L.
הוצא לאור ב ACS Med Chem Lett (2018)

Discovery of MK-8722: A Systemic, Direct Pan-Activator of AMP-Activated Protein Kinase

מאת Feng, Danqing, Biftu, Tesfaye, Romero, F. Anthony, Kekec, Ahmet, Dropinski, James, Kassick, Andrew, Xu, Shiyao, Kurtz, Marc M., Gollapudi, Anantha, Shao, Qing, Yang, Xiaodong, Lu, Ku, Zhou, Gaochao, Kemp, Daniel, Myers, Robert W., Guan, Hong-Ping, Trujillo, Maria E., Li, Cai, Weber, Ann, Sebhat, Iyassu K.
הוצא לאור ב ACS Med Chem Lett (2017)

GNE-886: A Potent and Selective Inhibitor of the Cat Eye Syndrome Chromosome Region Candidate 2 Bromodomain (CECR2)

מאת Crawford, Terry D., Audia, James E., Bellon, Steve, Burdick, Daniel J., Bommi-Reddy, Archana, Côté, Alexandre, Cummings, Richard T., Duplessis, Martin, Flynn, E. Megan, Hewitt, Michael, Huang, Hon-Ren, Jayaram, Hariharan, Jiang, Ying, Joshi, Shivangi, Kiefer, James R., Murray, Jeremy, Nasveschuk, Christopher G., Neiss, Arianne, Pardo, Eneida, Romero, F. Anthony, Sandy, Peter, Sims, Robert J., Tang, Yong, Taylor, Alexander M., Tsui, Vickie, Wang, Jian, Wang, Shumei, Wang, Yongyun, Xu, Zhaowu, Zawadzke, Laura, Zhu, Xiaoqin, Albrecht, Brian K., Magnuson, Steven R., Cochran, Andrea G.
הוצא לאור ב ACS Med Chem Lett (2017)

Regulatory T Cell Modulation by CBP/EP300 Bromodomain Inhibition

מאת Ghosh, Srimoyee, Taylor, Alexander, Chin, Melissa, Huang, Hon-Ren, Conery, Andrew R., Mertz, Jennifer A., Salmeron, Andres, Dakle, Pranal J., Mele, Deanna, Cote, Alexandre, Jayaram, Hari, Setser, Jeremy W., Poy, Florence, Hatzivassiliou, Georgia, DeAlmeida-Nagata, Denise, Sandy, Peter, Hatton, Charlie, Romero, F. Anthony, Chiang, Eugene, Reimer, Thornik, Crawford, Terry, Pardo, Eneida, Watson, Venita G., Tsui, Vickie, Cochran, Andrea G., Zawadzke, Laura, Harmange, Jean-Christophe, Audia, James E., Bryant, Barbara M., Cummings, Richard T., Magnuson, Steven R., Grogan, Jane L., Bellon, Steve F., Albrecht, Brian K., Sims, Robert J., Lora, Jose M.
הוצא לאור ב J Biol Chem (2016)

Fragment-Based Discovery of a Selective and Cell-Active Benzodiazepinone CBP/EP300 Bromodomain Inhibitor (CPI-637)

מאת Taylor, Alexander M., Côté, Alexandre, Hewitt, Michael C., Pastor, Richard, Leblanc, Yves, Nasveschuk, Christopher G., Romero, F. Anthony, Crawford, Terry D., Cantone, Nico, Jayaram, Hariharan, Setser, Jeremy, Murray, Jeremy, Beresini, Maureen H., de Leon Boenig, Gladys, Chen, Zhongguo, Conery, Andrew R., Cummings, Richard T., Dakin, Leslie A., Flynn, E. Megan, Huang, Oscar W., Kaufman, Susan, Keller, Patricia J., Kiefer, James R., Lai, Tommy, Li, Yingjie, Liao, Jiangpeng, Liu, Wenfeng, Lu, Henry, Pardo, Eneida, Tsui, Vickie, Wang, Jian, Wang, Yongyun, Xu, Zhaowu, Yan, Fen, Yu, Dong, Zawadzke, Laura, Zhu, Xiaoqin, Zhu, Xiaoyu, Sims, Robert J., Cochran, Andrea G., Bellon, Steve, Audia, James E., Magnuson, Steven, Albrecht, Brian K.
הוצא לאור ב ACS Med Chem Lett (2016)