Discovery of GNE-149 as a Full Antagonist and Efficient Degrader of Estrogen Receptor alpha for ER+ Breast Cancer

le Liang, Jun, Blake, Robert, Chang, Jae, Friedman, Lori S., Goodacre, Simon, Hartman, Steven, Ingalla, Ellen Rei, Kiefer, James R., Kleinheinz, Tracy, Labadie, Sharada, Li, Jun, Lai, Kwong Wah, Liao, Jiangpeng, Mody, Vidhi, McLean, Neville, Metcalfe, Ciara, Nannini, Michelle, Otwine, Daniel, Ran, Yingqing, Ray, Nick, Roussel, Fabien, Sambrone, Amy, Sampath, Deepak, Vinogradova, Maia, Wai, John, Wang, Tao, Yeap, Kuen, Young, Amy, Zbieg, Jason, Zhang, Birong, Zheng, Xiaoping, Zhong, Yu, Wang, Xiaojing
Foilsithe in ACS Med Chem Lett (2020)

Fragment-Based Discovery of a Selective and Cell-Active Benzodiazepinone CBP/EP300 Bromodomain Inhibitor (CPI-637)

le Taylor, Alexander M., Côté, Alexandre, Hewitt, Michael C., Pastor, Richard, Leblanc, Yves, Nasveschuk, Christopher G., Romero, F. Anthony, Crawford, Terry D., Cantone, Nico, Jayaram, Hariharan, Setser, Jeremy, Murray, Jeremy, Beresini, Maureen H., de Leon Boenig, Gladys, Chen, Zhongguo, Conery, Andrew R., Cummings, Richard T., Dakin, Leslie A., Flynn, E. Megan, Huang, Oscar W., Kaufman, Susan, Keller, Patricia J., Kiefer, James R., Lai, Tommy, Li, Yingjie, Liao, Jiangpeng, Liu, Wenfeng, Lu, Henry, Pardo, Eneida, Tsui, Vickie, Wang, Jian, Wang, Yongyun, Xu, Zhaowu, Yan, Fen, Yu, Dong, Zawadzke, Laura, Zhu, Xiaoqin, Zhu, Xiaoyu, Sims, Robert J., Cochran, Andrea G., Bellon, Steve, Audia, James E., Magnuson, Steven, Albrecht, Brian K.
Foilsithe in ACS Med Chem Lett (2016)