Diketo acid inhibitor mechanism and HIV-1 integrase: Implications for metal binding in the active site of phosphotransferase enzymes

Por Grobler, Jay A., Stillmock, Kara, Hu, Binghua, Witmer, Marc, Felock, Peter, Espeseth, Amy S., Wolfe, Abigail, Egbertson, Melissa, Bourgeois, Michele, Melamed, Jeffrey, Wai, John S., Young, Steve, Vacca, Joseph, Hazuda, Daria J.
Publicado em 2002

Linker Immolation Determines Cell Killing Activity of Disulfide-Linked Pyrrolobenzodiazepine Antibody–Drug Conjugates

Por Zhang, Donglu, Pillow, Thomas H., Ma, Yong, Cruz-Chuh, Josefa dela, Kozak, Katherine R., Sadowsky, Jack D., Lewis Phillips, Gail D., Guo, Jun, Darwish, Martine, Fan, Peter, Chen, Jingtian, He, Changrong, Wang, Tao, Yao, Hui, Xu, Zijin, Chen, Jinhua, Wai, John, Pei, Zhonghua, Hop, Cornelis E. C. A., Khojasteh, S. Cyrus, Dragovich, Peter S.
Publicado no ACS Med Chem Lett (2016)

Stabilizing a Tubulysin Antibody–Drug Conjugate To Enable Activity Against Multidrug-Resistant Tumors

Por Staben, Leanna R., Yu, Shang-Fan, Chen, Jinhua, Yan, Gang, Xu, Zijin, Del Rosario, Geoffrey, Lau, Jeffrey T., Liu, Luna, Guo, Jun, Zheng, Bing, Cruz-Chuh, Josefa dela, Lee, Byoung-Chul, Ohri, Rachana, Cai, Wenwen, Zhou, Hongxiang, Kozak, Katherine R., Xu, Keyang, Lewis Phillips, Gail D., Lu, Jiawei, Wai, John, Polson, Andrew G., Pillow, Thomas H.
Publicado no ACS Med Chem Lett (2017)

Effect of Suberoylanilide Hydroxamic Acid (SAHA) Administration on the Residual Virus Pool in a Model of Combination Antiretroviral Therapy-Mediated Suppression in SIVmac239-Infect...

Por Del Prete, Gregory Q., Shoemaker, Rebecca, Oswald, Kelli, Lara, Abigail, Trubey, Charles M., Fast, Randy, Schneider, Douglas K., Kiser, Rebecca, Coalter, Vicky, Wiles, Adam, Wiles, Rodney, Freemire, Brandi, Keele, Brandon F., Estes, Jacob D., Quiñones, Octavio A., Smedley, Jeremy, Macallister, Rhonda, Sanchez, Rosa I., Wai, John S., Tan, Christopher M., Alvord, W. Gregory, Hazuda, Daria J., Piatak, Michael, Lifson, Jeffrey D.
Publicado no Antimicrob Agents Chemother (2014)

A naphthyridine carboxamide provides evidence for discordant resistance between mechanistically identical inhibitors of HIV-1 integrase

Por Hazuda, Daria J., Anthony, Neville J., Gomez, Robert P., Jolly, Samson M., Wai, John S., Zhuang, Linghang, Fisher, Thorsten E., Embrey, Mark, Guare, James P., Egbertson, Melissa S., Vacca, Joseph P., Huff, Joel R., Felock, Peter J., Witmer, Marc V., Stillmock, Kara A., Danovich, Robert, Grobler, Jay, Miller, Michael D., Espeseth, Amy S., Jin, Lixia, Chen, I-Wu, Lin, Jiunn H., Kassahun, Kelem, Ellis, Joan D., Wong, Bradley K., Xu, Wei, Pearson, Paul G., Schleif, William A., Cortese, Riccardo, Emini, Emilio, Summa, Vincenzo, Holloway, M. Katharine, Young, Steven D.
Publicado em 2004