Overcoming multidrug resistance of small-molecule therapeutics through conjugation with releasable octaarginine transporters

ανά Dubikovskaya, Elena A., Thorne, Steve H., Pillow, Thomas H., Contag, Christopher H., Wender, Paul A.
Έκδοση 2008

The design of guanidinium-rich transporters and their internalization mechanisms

ανά Wender, Paul A., Galliher, Wesley C., Goun, Elena A., Jones, Lisa R., Pillow, Thomas H.
Έκδοση 2007

Taxol-Oligoarginine Conjugates Overcome Drug Resistance in-vitro in Human Ovarian Carcinoma

ανά Wender, Paul A., Galliher, Wesley C., Bhat, Neelima M., Pillow, Thomas H., Bieber, Marcia M., Teng, Nelson N. H.
Έκδοση 2012

Real-time analysis of uptake and bioactivatable cleavage of luciferin-transporter conjugates in transgenic reporter mice

ανά Wender, Paul A., Goun, Elena A., Jones, Lisa R., Pillow, Thomas H., Rothbard, Jonathan B., Shinde, Rajesh, Contag, Christopher H.
Έκδοση 2007

Decoupling stability and release in disulfide bonds with antibody-small molecule conjugates

ανά Pillow, Thomas H., Sadowsky, Jack D., Zhang, Donglu, Yu, Shang-Fan, Del Rosario, Geoffrey, Xu, Keyang, He, Jintang, Bhakta, Sunil, Ohri, Rachana, Kozak, Katherine R., Ha, Edward, Junutula, Jagath R., Flygare, John A.
Τόπος έκδοσης Chem Sci (2017)

Chemical Structure and Concentration of Intratumor Catabolites Determine Efficacy of Antibody Drug Conjugates

ανά Zhang, Donglu, Yu, Shang-Fan, Ma, Yong, Xu, Keyang, Dragovich, Peter S., Pillow, Thomas H., Liu, Luna, Del Rosario, Geoffrey, He, Jintang, Pei, Zhonghua, Sadowsky, Jack D., Erickson, Hans K., Hop, Cornelis E. C. A., Khojasteh, S. Cyrus
Τόπος έκδοσης Drug Metab Dispos (2016)

Improved translation of stability for conjugated antibodies using an in vitro whole blood assay

ανά Fourie-O’Donohue, Aimee, Chu, Phillip Y., dela Cruz Chuh, Josefa, Tchelepi, Robert, Tsai, Siao Ping, Tran, John C., Sawyer, William S., Su, Dian, Ng, Carl, Xu, Keyang, Yu, Shang-Fan, Pillow, Thomas H., Sadowsky, Jack, Dragovich, Peter S., Liu, Yichin, Kozak, Katherine R.
Τόπος έκδοσης MAbs (2020)

Linker Immolation Determines Cell Killing Activity of Disulfide-Linked Pyrrolobenzodiazepine Antibody–Drug Conjugates

ανά Zhang, Donglu, Pillow, Thomas H., Ma, Yong, Cruz-Chuh, Josefa dela, Kozak, Katherine R., Sadowsky, Jack D., Lewis Phillips, Gail D., Guo, Jun, Darwish, Martine, Fan, Peter, Chen, Jingtian, He, Changrong, Wang, Tao, Yao, Hui, Xu, Zijin, Chen, Jinhua, Wai, John, Pei, Zhonghua, Hop, Cornelis E. C. A., Khojasteh, S. Cyrus, Dragovich, Peter S.
Τόπος έκδοσης ACS Med Chem Lett (2016)

Stabilizing a Tubulysin Antibody–Drug Conjugate To Enable Activity Against Multidrug-Resistant Tumors

ανά Staben, Leanna R., Yu, Shang-Fan, Chen, Jinhua, Yan, Gang, Xu, Zijin, Del Rosario, Geoffrey, Lau, Jeffrey T., Liu, Luna, Guo, Jun, Zheng, Bing, Cruz-Chuh, Josefa dela, Lee, Byoung-Chul, Ohri, Rachana, Cai, Wenwen, Zhou, Hongxiang, Kozak, Katherine R., Xu, Keyang, Lewis Phillips, Gail D., Lu, Jiawei, Wai, John, Polson, Andrew G., Pillow, Thomas H.
Τόπος έκδοσης ACS Med Chem Lett (2017)

Preclinical optimization of Ly6E-targeted ADCs for increased durability and efficacy of anti-tumor response

ανά Dela Cruz Chuh, Josefa, Go, MaryAnn, Chen, Yvonne, Guo, Jun, Rafidi, Hanine, Mandikian, Danielle, Sun, Yonglian, Lin, Zhonghua, Schneider, Kellen, Zhang, Pamela, Vij, Rajesh, Sharpnack, Danielle, Chan, Pamela, de la Cruz, Cecile, Sadowsky, Jack, Seshasayee, Dhaya, Koerber, James T., Pillow, Thomas H., Phillips, Gail D., Rowntree, Rebecca K, Boswell, C. Andrew, Kozak, Katherine R., Polson, Andrew G., Polakis, Paul, Yu, Shang-Fan, Dragovich, Peter S., Agard, Nicholas J.
Τόπος έκδοσης MAbs (2020)