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The design of guanidinium-rich transporters and their internalization mechanisms
The ability of a drug or probe to cross a biological barrier has historically been viewed to be a function of its intrinsic physical properties. This view has largely restricted drug design and selection to agents within a narrow log P range. Molecular transporters offer a strategy to circumvent the...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2007
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2533582/ https://ncbi.nlm.nih.gov/pubmed/18164781 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.addr.2007.10.016 |
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