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Taxol-Oligoarginine Conjugates Overcome Drug Resistance in-vitro in Human Ovarian Carcinoma
OBJECTIVE: Multidrug resistance is the major cause of failure of many chemotherapeutic agents. While resistance can arise from several factors, it is often dominated by drug efflux mediated by P-glycoprotein (P-gp), a membrane-bound polysubstrate export pump expressed at high levels in resistant cel...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3883629/ https://ncbi.nlm.nih.gov/pubmed/22484398 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ygyno.2012.03.049 |
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