Llwytho...

Optimization of α-Ketooxazole Inhibitors of Fatty Acid Amide Hydrolase

A series of α-ketooxazoles containing conformational constraints in the flexible C2 acyl side chain of 2 (OL-135) and representative oxazole C5 substituents was prepared and examined as inhibitors of fatty acid amide hydrolase (FAAH). Exceptionally potent and selective FAAH inhibitors emerged from t...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Kimball, F. Scott, Romero, F. Anthony, Ezzili, Cyrine, Garfunkle, Joie, Rayl, Thomas J., Hochstatter, Dustin G., Hwang, Inkyu, Boger, Dale L.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2008
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2734917/
https://ncbi.nlm.nih.gov/pubmed/18247553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm701210y
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!