Identification of a transcriptional repressor related to the noncatalytic domain of histone deacetylases 4 and 5

gan Zhou, Xianbo, Richon, Victoria M., Rifkind, Richard A., Marks, Paul A.
Cyhoeddwyd 2000

Cloning and characterization of a histone deacetylase, HDAC9

gan Zhou, Xianbo, Marks, Paul A., Rifkind, Richard A., Richon, Victoria M.
Cyhoeddwyd 2001

Histone deacetylase inhibitor selectively induces p21(WAF1) expression and gene-associated histone acetylation

gan Richon, Victoria M., Sandhoff, Todd W., Rifkind, Richard A., Marks, Paul A.
Cyhoeddwyd 2000

Histone deacetylase 4 associates with extracellular signal-regulated kinases 1 and 2, and its cellular localization is regulated by oncogenic Ras

gan Zhou, Xianbo, Richon, Victoria M., Wang, Audrey H., Yang, Xiang-Jiao, Rifkind, Richard A., Marks, Paul A.
Cyhoeddwyd 2000

A class of hybrid polar inducers of transformed cell differentiation inhibits histone deacetylases

gan Richon, Victoria M., Emiliani, Stephane, Verdin, Eric, Webb, Yael, Breslow, Ronald, Rifkind, Richard A., Marks, Paul A.
Cyhoeddwyd 1998

Antileukemia activity of the combination of an anthracycline with a histone deacetylase inhibitor

gan Sanchez-Gonzalez, Blanca, Yang, Hui, Bueso-Ramos, Carlos, Hoshino, Koyu, Quintas-Cardama, Alfonso, Richon, Victoria M., Garcia-Manero, Guillermo
Cyhoeddwyd 2006

The histone deacetylase inhibitor SAHA arrests cancer cell growth, up-regulates thioredoxin-binding protein-2, and down-regulates thioredoxin

gan Butler, Lisa M., Zhou, Xianbo, Xu, Wei-Sheng, Scher, Howard I., Rifkind, Richard A., Marks, Paul A., Richon, Victoria M.
Cyhoeddwyd 2002

Vorinostat in solid and hematologic malignancies

gan Siegel, David, Hussein, Mohamad, Belani, Chandra, Robert, Francisco, Galanis, Evanthia, Richon, Victoria M, Garcia-Vargas, José, Sanz-Rodriguez, Cesar, Rizvi, Syed
Cyhoeddwyd 2009

Coordinated activities of wild-type plus mutant EZH2 drive tumor-associated hypertrimethylation of lysine 27 on histone H3 (H3K27) in human B-cell lymphomas

gan Sneeringer, Christopher J., Scott, Margaret Porter, Kuntz, Kevin W., Knutson, Sarah K., Pollock, Roy M., Richon, Victoria M., Copeland, Robert A.
Cyhoeddwyd 2010

Histone deacetylase inhibitors induce remission in transgenic models of therapy-resistant acute promyelocytic leukemia

gan He, Li-Zhen, Tolentino, Thomas, Grayson, Peter, Zhong, Sue, Warrell, Raymond P., Rifkind, Richard A., Marks, Paul A., Richon, Victoria M., Pandolfi, Pier Paolo
Cyhoeddwyd 2001

Identification and functional significance of genes regulated by structurally different histone deacetylase inhibitors

gan Peart, Melissa J., Smyth, Gordon K., van Laar, Ryan K., Bowtell, David D., Richon, Victoria M., Marks, Paul A., Holloway, Andrew J., Johnstone, Ricky W.
Cyhoeddwyd 2005

Phase 2 trial of oral vorinostat (suberoylanilide hydroxamic acid, SAHA) for refractory cutaneous T-cell lymphoma (CTCL)

gan Duvic, Madeleine, Talpur, Rakshandra, Ni, Xiao, Zhang, Chunlei, Hazarika, Parul, Kelly, Cecilia, Chiao, Judy H., Reilly, John F., Ricker, Justin L., Richon, Victoria M., Frankel, Stanley R.
Cyhoeddwyd 2007

Abrogation of MLL-AF10 and CALM-AF10 mediated transformation through genetic inactivation or pharmacological inhibition of the H3K79 methyltransferase Dot1l

gan Chen, Liying, Deshpande, Aniruddha, Banka, Deepti, Bernt, Kathrin M., Dias, Stuart, Buske, Christian, Olhava, Edward J., Daigle, Scott R., Richon, Victoria M., Pollock, Roy M., Armstrong, Scott A.
Cyhoeddwyd 2012

Leukemic transformation by the MLL-AF6 fusion oncogene requires the H3K79 methyltransferase Dot1l

gan Deshpande, Aniruddha J., Chen, Liying, Fazio, Maurizio, Sinha, Amit U., Bernt, Kathrin M., Banka, Deepti, Dias, Stuart, Chang, Jenny, Olhava, Edward J., Daigle, Scott R., Richon, Victoria M., Pollock, Roy M., Armstrong, Scott A.
Cyhoeddwyd 2013

MLL-rearranged Leukemia is Dependent on Aberrant H3K79 Methylation by DOT1L

gan Bernt, Kathrin M., Zhu, Nan, Sinha, Amit U., Vempati, Sridhar, Faber, Joerg, Krivtsov, Andrei V., Feng, Zhaohui, Punt, Natalie, Daigle, Amanda, Bullinger, Lars, Pollock, Roy M., Richon, Victoria M., Kung, Andrew L., Armstrong, Scott A.
Cyhoeddwyd 2011

Transcriptional signature of histone deacetylase inhibition in multiple myeloma: Biological and clinical implications

gan Mitsiades, Constantine S., Mitsiades, Nicholas S., McMullan, Ciaran J., Poulaki, Vassiliki, Shringarpure, Reshma, Hideshima, Teru, Akiyama, Masaharu, Chauhan, Dharminder, Munshi, Nikhil, Gu, Xuesong, Bailey, Charles, Joseph, Marie, Libermann, Towia A., Richon, Victoria M., Marks, Paul A., Anderson, Kenneth C.
Cyhoeddwyd 2004

Durable tumor regression in genetically altered malignant rhabdoid tumors by inhibition of methyltransferase EZH2

gan Knutson, Sarah K., Warholic, Natalie M., Wigle, Tim J., Klaus, Christine R., Allain, Christina J., Raimondi, Alejandra, Porter Scott, Margaret, Chesworth, Richard, Moyer, Mikel P., Copeland, Robert A., Richon, Victoria M., Pollock, Roy M., Kuntz, Kevin W., Keilhack, Heike
Cyhoeddwyd 2013

Suberoylanilide hydroxamic acid, a histone deacetylase inhibitor, ameliorates motor deficits in a mouse model of Huntington's disease

gan Hockly, Emma, Richon, Victoria M., Woodman, Benjamin, Smith, Donna L., Zhou, Xianbo, Rosa, Eddie, Sathasivam, Kirupa, Ghazi-Noori, Shabnam, Mahal, Amarbirpal, Lowden, Philip A. S., Steffan, Joan S., Marsh, J. Lawrence, Thompson, Leslie M., Lewis, Cathryn M., Marks, Paul A., Bates, Gillian P.
Cyhoeddwyd 2003

Phase I Study of an Oral Histone Deacetylase Inhibitor, Suberoylanilide Hydroxamic Acid, in Patients With Advanced Cancer

gan Kelly, William Kevin, O’Connor, Owen A., Lee Krug, M., Chiao, Judy H., Heaney, Mark, Curley, Tracy, MacGregore-Cortelli, Barbara, Tong, William, Secrist, J. Paul, Schwartz, Lawrence, Richardson, Stacy, Chu, Elaina, Olgac, Semra, Marks, Paul A., Scher, Howard, Richon, Victoria M.
Cyhoeddwyd 2005

Phase II Trial of Vorinostat in Recurrent Glioblastoma Multiforme: A North Central Cancer Treatment Group Study

gan Galanis, Evanthia, Jaeckle, Kurt A., Maurer, Matthew J., Reid, Joel M., Ames, Matthew M., Hardwick, James S., Reilly, John F., Loboda, Andrey, Nebozhyn, Michael, Fantin, Valeria R., Richon, Victoria M., Scheithauer, Bernd, Giannini, Caterina, Flynn, Patrick J., Moore, Dennis F., Zwiebel, James, Buckner, Jan C.
Cyhoeddwyd 2009