Role of crosslinking for agonistic CD40 monoclonal antibodies as immune therapy of cancer

অনুযায়ী Richman, Lee P., Vonderheide, Robert H.
প্রকাশিত 2013

Anti-human CD40 monoclonal antibody therapy is potent without FcR crosslinking

অনুযায়ী Richman, Lee P, Vonderheide, Robert H
প্রকাশিত 2014

Neoantigen dissimilarity to the self-proteome predicts immunogenicity and response to immune checkpoint blockade

অনুযায়ী Richman, Lee P., Vonderheide, Robert H., Rech, Andrew J.
প্রকাশিত Cell Syst (2019)

Toll-like receptor 9 and Interferon-γ receptor signaling suppress the B-cell fate of uncommitted progenitors in mice

অনুযায়ী Baratono, Sheena R., Chu, Niansheng, Richman, Lee P., Behrens, Edward M.
প্রকাশিত Eur J Immunol (2015)

Pharmacodynamic monitoring predicts outcomes of CCR5 blockade as GVHD prophylaxis

অনুযায়ী Huffman, Austin P., Richman, Lee P., Crisalli, Lisa, Ganetsky, Alex, Porter, David L., Vonderheide, Robert H., Reshef, Ran
প্রকাশিত Biol Blood Marrow Transplant (2017)

NKG2D expression by CD8(+) T cells contributes to GVHD and GVT effects in a murine model of allogeneic HSCT

অনুযায়ী Karimi, Mobin A., Bryson, Jerrod L., Richman, Lee P., Fesnak, Andrew D., Leichner, Theresa M., Satake, Atsushi, Vonderheide, Robert H., Raulet, David H., Reshef, Ran, Kambayashi, Taku
প্রকাশিত Blood (2015)

Cancer Immunology Miniatures: Immune activation and a 9-year ongoing complete remission following CD40 antibody therapy and metastasectomy in a patient with metastatic melanoma

অনুযায়ী Bajor, David L., Xu, Xiaowei, Torigian, Drew A., Mick, Rosemarie, Garcia, Laura R., Richman, Lee P., Desmarais, Cindy, Nathanson, Katherine L., Schuchter, Lynn M., Kalos, Michael, Vonderheide, Robert H.
প্রকাশিত Cancer Immunol Res (2014)

Clinical and immunologic impact of CCR5 blockade in graft-versus-host disease prophylaxis

অনুযায়ী Moy, Ryan H., Huffman, Austin P., Richman, Lee P., Crisalli, Lisa, Wang, Ximi K., Hoxie, James A., Mick, Rosemarie, Emerson, Stephen G., Zhang, Yi, Vonderheide, Robert H., Porter, David L., Reshef, Ran
প্রকাশিত Blood (2017)

Antifibrotic Effects of the Dual CCR2/CCR5 Antagonist Cenicriviroc in Animal Models of Liver and Kidney Fibrosis

অনুযায়ী Lefebvre, Eric, Moyle, Graeme, Reshef, Ran, Richman, Lee P., Thompson, Melanie, Hong, Feng, Chou, Hsin-l, Hashiguchi, Taishi, Plato, Craig, Poulin, Dominic, Richards, Toni, Yoneyama, Hiroyuki, Jenkins, Helen, Wolfgang, Grushenka, Friedman, Scott L.
প্রকাশিত PLoS One (2016)

Tumor cell–intrinsic EPHA2 suppresses antitumor immunity by regulating PTGS2 (COX-2)

অনুযায়ী Markosyan, Nune, Li, Jinyang, Sun, Yu H., Richman, Lee P., Lin, Jeffrey H., Yan, Fangxue, Quinones, Liz, Sela, Yogev, Yamazoe, Taiji, Gordon, Naomi, Tobias, John W., Byrne, Katelyn T., Rech, Andrew J., FitzGerald, Garret A., Stanger, Ben Z., Vonderheide, Robert H.
প্রকাশিত J Clin Invest (2019)

High Graft CD8 Cell Dose Predicts Improved Survival and Enables Better Donor Selection in Allogeneic Stem-Cell Transplantation With Reduced-Intensity Conditioning

অনুযায়ী Reshef, Ran, Huffman, Austin P., Gao, Amy, Luskin, Marlise R., Frey, Noelle V., Gill, Saar I., Hexner, Elizabeth O., Kambayashi, Taku, Loren, Alison W., Luger, Selina M., Mangan, James K., Nasta, Sunita D., Richman, Lee P., Sell, Mary, Stadtmauer, Edward A., Vonderheide, Robert H., Mick, Rosemarie, Porter, David L.
প্রকাশিত J Clin Oncol (2015)

Long-term outcomes of a phase I study of agonist CD40 antibody and CTLA-4 blockade in patients with metastatic melanoma

অনুযায়ী Bajor, David L., Mick, Rosemarie, Riese, Matthew J., Huang, Alex C., Sullivan, Brendan, Richman, Lee P., Torigian, Drew A., George, Sangeeth M., Stelekati, Erietta, Chen, Fang, Melenhorst, J. Joseph, Lacey, Simon F., Xu, Xiaowei, Wherry, E. John, Gangadhar, Tara C., Amaravadi, Ravi K., Schuchter, Lynn M., Vonderheide, Robert H.
প্রকাশিত Oncoimmunology (2018)

Biochemical and functional characterization of mutant KRAS epitopes validates this oncoprotein for immunological targeting

অনুযায়ী Bear, Adham S., Blanchard, Tatiana, Cesare, Joseph, Ford, Michael J., Richman, Lee P., Xu, Chong, Baroja, Miren L., McCuaig, Sarah, Costeas, Christina, Gabunia, Khatuna, Scholler, John, Posey, Avery D., O’Hara, Mark H., Smole, Anze, Powell, Daniel J., Garcia, Benjamin A., Vonderheide, Robert H., Linette, Gerald P., Carreno, Beatriz M.
প্রকাশিত Nat Commun (2021)

Infusion of CD3/CD28 costimulated umbilical cord blood T cells at the time of single umbilical cord blood transplantation may enhance engraftment

অনুযায়ী Hexner, Elizabeth O., Luger, Selina M., Reshef, Ran, Jeschke, Grace R., Mangan, James K., Frey, Noelle V., Frank, Dale M., Richman, Lee P., Vonderheide, Robert H., Aqui, Nicole A., Rosenbach, Misha, Zhang, Yi, Chew, Anne, Loren, Alison W., Stadtmauer, Edward A., Levine, Bruce L., June, Carl H., Emerson, Stephen G., Porter, David L.
প্রকাশিত Am J Hematol (2016)

Human Treg responses allow sustained recombinant adeno-associated virus–mediated transgene expression

অনুযায়ী Mueller, Christian, Chulay, Jeffrey D., Trapnell, Bruce C., Humphries, Margaret, Carey, Brenna, Sandhaus, Robert A., McElvaney, Noel G., Messina, Louis, Tang, Qiushi, Rouhani, Farshid N., Campbell-Thompson, Martha, Fu, Ann Dongtao, Yachnis, Anthony, Knop, David R., Ye, Guo-jie, Brantly, Mark, Calcedo, Roberto, Somanathan, Suryanarayan, Richman, Lee P., Vonderheide, Robert H., Hulme, Maigan A., Brusko, Todd M., Wilson, James M., Flotte, Terence R.
প্রকাশিত 2013

CCR5-edited CD4(+) T cells augment HIV-specific immunity to enable post-rebound control of HIV replication

অনুযায়ী Tebas, Pablo, Jadlowsky, Julie K., Shaw, Pamela A., Tian, Lifeng, Esparza, Erin, Brennan, Andrea L., Kim, Sukyung, Naing, Soe Yu, Richardson, Max W., Vogel, Ashley N., Maldini, Colby R., Kong, Hong, Liu, Xiaojun, Lacey, Simon F., Bauer, Anya M., Mampe, Felicity, Richman, Lee P., Lee, Gary, Ando, Dale, Levine, Bruce L., Porter, David L., Zhao, Yangbing, Siegel, Don L., Bar, Katharine J., June, Carl H., Riley, James L.
প্রকাশিত J Clin Invest (2021)

Tumor cell-intrinsic factors underlie heterogeneity of immune cell infiltration and response to immunotherapy

অনুযায়ী Li, Jinyang, Byrne, Katelyn T., Yan, Fangxue, Yamazoe, Taiji, Chen, Zeyu, Baslan, Timour, Richman, Lee P., Lin, Jeffrey, Sun, Yu H., Rech, Andrew J., Balli, David, Hay, Ceire A., Sela, Yogev, Merrell, Allyson J., Liudahl, Shannon M., Gordon, Naomi, Norgard, Robert J., Yuan, Salina, Yu, Sixiang, Chao, Timothy, Ye, Shuai, Eisinger-Mathason, T.S. Karin, Faryabi, Robert B., Tobias, John W., Lowe, Scott, Coussens, Lisa M., Wherry, E. John, Vonderheide, Robert H., Stanger, Ben Z.
প্রকাশিত Immunity (2018)