Antifibrotic Effects of the Dual CCR2/CCR5 Antagonist Cenicriviroc in Animal Models of Liver and Kidney Fibrosis

BACKGROUND & AIMS: Interactions between C-C chemokine receptor types 2 (CCR2) and 5 (CCR5) and their ligands, including CCL2 and CCL5, mediate fibrogenesis by promoting monocyte/macrophage recruitment and tissue infiltration, as well as hepatic stellate cell activation. Cenicriviroc (CVC) is an...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Lefebvre, Eric, Moyle, Graeme, Reshef, Ran, Richman, Lee P., Thompson, Melanie, Hong, Feng, Chou, Hsin-l, Hashiguchi, Taishi, Plato, Craig, Poulin, Dominic, Richards, Toni, Yoneyama, Hiroyuki, Jenkins, Helen, Wolfgang, Grushenka, Friedman, Scott L.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4922569/
https://ncbi.nlm.nih.gov/pubmed/27347680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0158156
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker