Tumor cell-intrinsic factors underlie heterogeneity of immune cell infiltration and response to immunotherapy

The biological and functional heterogeneity between tumors – both across and within cancer types – poses a challenge for immunotherapy. To understand the factors underlying tumor immune heterogeneity and immunotherapy sensitivity, we established a library of congenic tumor cell clones from an autoch...

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Detalhes bibliográficos
Publicado no:Immunity
Main Authors: Li, Jinyang, Byrne, Katelyn T., Yan, Fangxue, Yamazoe, Taiji, Chen, Zeyu, Baslan, Timour, Richman, Lee P., Lin, Jeffrey, Sun, Yu H., Rech, Andrew J., Balli, David, Hay, Ceire A., Sela, Yogev, Merrell, Allyson J., Liudahl, Shannon M., Gordon, Naomi, Norgard, Robert J., Yuan, Salina, Yu, Sixiang, Chao, Timothy, Ye, Shuai, Eisinger-Mathason, T.S. Karin, Faryabi, Robert B., Tobias, John W., Lowe, Scott, Coussens, Lisa M., Wherry, E. John, Vonderheide, Robert H., Stanger, Ben Z.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6707727/
https://ncbi.nlm.nih.gov/pubmed/29958801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2018.06.006
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