Clinical and immunologic impact of CCR5 blockade in graft-versus-host disease prophylaxis

Graft-versus-host disease (GVHD) is a major cause of morbidity and mortality after allogeneic hematopoietic stem cell transplantation (allo-HSCT). Lymphocyte trafficking via chemokine receptors such as CCR5 plays a critical role in alloreactive responses, and previous data suggest that CCR5 blockade...

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Bibliografische gegevens
Gepubliceerd in:Blood
Hoofdauteurs: Moy, Ryan H., Huffman, Austin P., Richman, Lee P., Crisalli, Lisa, Wang, Ximi K., Hoxie, James A., Mick, Rosemarie, Emerson, Stephen G., Zhang, Yi, Vonderheide, Robert H., Porter, David L., Reshef, Ran
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society of Hematology 2017
Onderwerpen:
Transplantation
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5314813/
https://ncbi.nlm.nih.gov/pubmed/28057639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-08-735076
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