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Clinical and immunologic impact of CCR5 blockade in graft-versus-host disease prophylaxis

Graft-versus-host disease (GVHD) is a major cause of morbidity and mortality after allogeneic hematopoietic stem cell transplantation (allo-HSCT). Lymphocyte trafficking via chemokine receptors such as CCR5 plays a critical role in alloreactive responses, and previous data suggest that CCR5 blockade...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Moy, Ryan H., Huffman, Austin P., Richman, Lee P., Crisalli, Lisa, Wang, Ximi K., Hoxie, James A., Mick, Rosemarie, Emerson, Stephen G., Zhang, Yi, Vonderheide, Robert H., Porter, David L., Reshef, Ran
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5314813/
https://ncbi.nlm.nih.gov/pubmed/28057639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-08-735076
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