Clinical and immunologic impact of CCR5 blockade in graft-versus-host disease prophylaxis

Graft-versus-host disease (GVHD) is a major cause of morbidity and mortality after allogeneic hematopoietic stem cell transplantation (allo-HSCT). Lymphocyte trafficking via chemokine receptors such as CCR5 plays a critical role in alloreactive responses, and previous data suggest that CCR5 blockade...

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Dettagli Bibliografici
Pubblicato in:Blood
Autori principali: Moy, Ryan H., Huffman, Austin P., Richman, Lee P., Crisalli, Lisa, Wang, Ximi K., Hoxie, James A., Mick, Rosemarie, Emerson, Stephen G., Zhang, Yi, Vonderheide, Robert H., Porter, David L., Reshef, Ran
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2017
Soggetti:
Transplantation
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5314813/
https://ncbi.nlm.nih.gov/pubmed/28057639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-08-735076
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