Clinical and immunologic impact of CCR5 blockade in graft-versus-host disease prophylaxis

Graft-versus-host disease (GVHD) is a major cause of morbidity and mortality after allogeneic hematopoietic stem cell transplantation (allo-HSCT). Lymphocyte trafficking via chemokine receptors such as CCR5 plays a critical role in alloreactive responses, and previous data suggest that CCR5 blockade...

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Bibliografiske detaljer
Udgivet i:Blood
Main Authors: Moy, Ryan H., Huffman, Austin P., Richman, Lee P., Crisalli, Lisa, Wang, Ximi K., Hoxie, James A., Mick, Rosemarie, Emerson, Stephen G., Zhang, Yi, Vonderheide, Robert H., Porter, David L., Reshef, Ran
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2017
Fag:
Transplantation
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5314813/
https://ncbi.nlm.nih.gov/pubmed/28057639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-08-735076
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