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Neoantigen dissimilarity to the self-proteome predicts immunogenicity and response to immune checkpoint blockade
Despite improved methods for MHC affinity prediction, the vast majority of computationally predicted tumor neoantigens are not immunogenic experimentally, indicating that high-quality neoantigens are beyond current algorithms to discern. To enrich for neoantigens with the greatest likelihood of immu...
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| Publicado en: | Cell Syst |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6813910/ https://ncbi.nlm.nih.gov/pubmed/31606370 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cels.2019.08.009 |
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